The Challange of Age Spot Treatments

By Dr Wendy Wells, NMD

Age spots, also known as, "hyperpigmentation," is a common skin condition present in all skin types. However, age spots are most evident in darker colored skin. Inflammation, or injury, can immediately result in the alteration of pigmentation, such as hyperpigmentation overdarkening, or hypopigmentation underdarkening.

Post-inflammatory hyperpigmentation, or darkened age spots, can occur in skin conditions such as:

Treatments can be challenging when attempting to reduce age spots without turing the skin to white or producing irritation in the surrounding area. Source: Semin Cutan Med Surg. 2011 Sep;30(3):171-5. PMID:21925372

Age Spot Removal Using Vitamin C and E

Vitamin C and E

In January 2012, the Journal of Drugs in Dermatology published evidence how topical Vitamin C can treat age spots that occur from sun overexposure. Skin treatment effects were shown using a 24% solution of Vitamin C (L-ascorbic acid) with iontophoresis. Iontophoresis is used as a penetration enhancer helping to prevent the oxidation of topical vitamin C. The study represented 20 participants, where sixteen of those participants showed a 2-3 grade improvement of pigmentation, surface roughness, and fine wrinkle lines.

The skin grading assessment used tools including, self-assessment, spectrophotometer, phase-shift measurement, and a corneometer. The researchers concluded that topical vitamin C (L-ascorbic acid) is safe and effective for the treatment and removal of age spots. Source: Journal of Drugs in Dermatology. 2012;11(1):51-56. PMID:22206077

Topical Antioxidant Protection Against Age Spots

Researchers from the University of Milan provided clinical evidence of a photoprotective effect of topical antioxidants vitamin E and A.

The Journal of Europe's Academy of Dermatology and Venereology pubished their work the September 2011 issue showing topical antioxidants can provide a photoprotective effect for treatment of age spots.

Topical Vitamin E, or Vitamin A ?

Vitamin E is an antioxidant that was among the first recognized. This study suggests that Vitamin A tocotrienols have superior effect over Vitamin E tocopherols. Vitamin A has become well-established in dermatology for its actions, including it's ability to absorb ultraviolet radiation.

The clinical results of the study:

"Pre-treatment with the vitamin E formulation highly protects against photosensitivity. Significantly lower reactions to irradiation in the areas treated with the topical vitamin E formulation, compared to those treated with a placebo or vitamin A."

Researchers concluded how the topical application which contain significant concentrations of Vitamin A tocotrienols and Vitamin E tocopherols represents an effective new approach to reducing photo-induced skin damage.PMID:21917024

Age Spot Removal: Folk Remedies

Check back, or bookmark us, as we work to publish the clinical evidence that either supports, or denies, the effects of the folk remedies listed below:

Forthcoming Articles:
Age Spot Removal | Liver Spots | Age Spots | Brown Spots | Sun Spots | Melasma | White Spots on Skin | Laser Treatment | Chemical Peels | Microdermabrasion | Cryosurgery | Creams | Cost and Pricing | Choosing a Doctor | FAQ's

Skin Cancer Resources

UV Radiation Map Save your skin. Get up-to-date ultraviolet radiation alerts.

The SHADE Foundation of America toeducate youth about sun safety and prevent melanoma. To learn more aboutSHADE and its SunWise program for schools, visit ShadeFoundation.org.

American Academy of Dermatology National Coalition for Sun Safety

Skin Cancer Foundation provides information about sun safety and skin cancer prevention.

Women'sDermatologic Society "Families Play Safe in the Sun" campaign.

Heartspring.net applauds the efforts of the Cancer Crusadersorganization in its mission to educate young adults.



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